مشخصات پژوهش

صفحه نخست /The effects of dietary 1, ...
عنوان
The effects of dietary 1, 25-dihydroxycholecalciferol and hydroalcoholic extract of Withania somnifera root on bone mineralisation, strength and histological characteristics in broiler chickens
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Withania somnifera, broiler chicken
چکیده
1. This study was carried out to investigate the effects of 1, 25-dihydroxycholecalciferol (1, 25 (OH)2 D3) and a hydroalcoholic extract of Withania somnifera (WS) root on performance, mineral retention, bone mineralisation, bone mechanical and bone histological characteristics of broiler chicks. 2. A 2 × 3 × 2 factorial experiment consisted of a positive control diet with adequate Ca and a negative control diet (Ca concentration reduced by 30%), three concentrations of WS (0, 75 and 150 mg/kg diet), and two concentrations of 1, 25 (OH)2 D3 (0 and 0.5 μg/kg diet). 3. A total of 600 male one-d-old Ross 308 broiler chicks were randomly distributed into 60 floor pens, with 10 birds each. Each treatment was replicated 5 times (50 birds). Diets were given ad libitum from one to 42 d of age. On d 21 and 42, one bird per replicate was killed and tibiae were removed. 4. Dietary treatments did not affect feed intake and feed conversion. The maximum body weight gain (2475 g) was noted in birds fed on a diet adequate in Ca and supplemented with 75 mg/kg WS. 5. The Ca and P retentions were significantly higher in birds that were given a diet with 30% less Ca. Supplementation of 150 mg/kg WS significantly improved Ca retention in birds receiving a negative control compared to those given a positive control diet (83.0% vs. 66.3%). Ca retention was significantly improved with the addition of 0.5 μg/kg 1, 25 (OH)2 D3 to the diet containing 75 mg/kg WS, regardless of dietary Ca concentration (79.5 vs. 73.3 and 77.9 vs. 68.9). 6. On d 21, birds that received WS had significantly higher tibia Ca compared to those of controls. No significant effects on tibia Ca were noted at 42 d. Birds given a negative control diet supplemented with 75 mg/kg WS and 0.5 μg/kg 1, 25 (OH)2 D3 displayed a similar tibia Ca compared to those given only 150 mg/kg WS. Dietary supplementation of 1, 25 (OH)2 D3 significantly increased tibia Ca and tibial mineralised zone width in birds at 42 d of age. 7. Tibia
پژوهشگران محمد طاهر میرکزهی (نفر اول)، حسن کرمانشاهی (نفر دوم)، ابوالقاسم گلیان (نفر سوم)، احمد رضا راجی (نفر چهارم)